Browsing by Author "Muzzalupo, Rita"

Now showing 1 - 3 of 3

Advanced and smart nanocarriers for pharmaceutical applications
(Università della Calabria, 2020-04-17) Mazzotta, Elisabetta; Andò, Sebastiano; Muzzalupo, Rita
The application of nanotechnology in drug formulation has made significant headway over the last decade. Nanoscale controlled release systems allow to revalue and reformulate old drugs through targeted delivery to the desired pathological site, improving therapeutic efficiency and reducing side effects. This innovative modality of drug delivery aims to create personalized, safer and effective treatments. A great interest of the academic and industrial research is focused on the design and development of advanced nanocarriers since is a profitable way in terms of costs, times and risks than the discovery of new drugs. Herein, an extensive variety of nanocarriers systems composed of different materials including lipids, polymers and non-ionic surfactants have been proposed for different pharmaceutical applications. Specifically, the carriers have been tailor-made designed to improve drug photostability, enhance skin permeation and realize smart tools for tumor target therapy.
Next-Generation vesicular systems in Nanomedicine: building blocks for personalized therapeutics
(Università della Calabria, 2024-05-21) Romeo, Martina; Catalano, Stefania; Muzzalupo, Rita
The emergence of nanotechnology has not only revolutionized the field of drug formulation but has also ushered in a new era of personalized therapeutic interventions. Over the past few years, nanoscale-controlled release systems have emerged as gamechangers, exhibiting extraordinary potential in augmenting therapeutic effectiveness while concurrently mitigating the adverse effects associated with traditional medications. This novel cohort of nanocarriers, comprising a rich array of materials including lipids, polymers, and non-ionic surfactants, stands as a testament to the versatility and ingenuity of nanotechnological advancements. By harnessing their unique properties, nanovehicles offer a precision-targeted approach to drug delivery, homing in on specific pathological sites with unprecedented accuracy. Moreover, the inherent adaptability of nanocarriers allows for bespoke modifications tailored to individual therapeutic needs, whether it be bolstering drug stability, facilitating permeation across biological barriers, or orchestrating sophisticated "intelligent" systems for targeted cancer therapy. Not only does this approach promise to enhance therapeutic outcomes, but it also presents a more efficient and cost-effective alternative to the traditional pursuit of novel pharmacologically active compounds. As such, the convergence of nanotechnology and drug delivery represents a compelling frontier in the quest for optimized therapeutic interventions, holding profound implications for the future of medicine.
Sintesi di biomateriali a base di cellulosa derivatizzata
(2008-10-07) Bloise, Ermelinda; Muzzalupo, Rita; Gabriele, Bartolo