Dipartimento di Biologia, Ecologia e Scienze della Terra - Tesi di dottorato
Permanent URI for this collectionhttps://lisa.unical.it/handle/10955/34
Questa collezione raccoglie le Tesi di Dottorato afferenti al Dipartimento Dipartimento di Biologia, Ecologia e Scienze della Terra dell'Università della Calabria.
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Item Adaptative response of Posidonia oceanica (L.) Delile leaves to salt water and to depth: PoPIP1;1 aquaporin involvement and anatomical strategies evolution(2009) Nicastro, Silvia; Musacchio, Aldo; Innocenti, Anna Maria; Giuseppe Passalacqua, Nicodemo GiuseppeItem Alterazioni morfo-funzionali del fegato e dell'apparato branchiale di zebrafish (Danio rerio) dopo esposizione a cloruro di mercurio(2017-06-09) Maricella, Rachele; Canonaco, Marcello; Brunelli, ElviraItem Alterazioni morfo-funzionali indotte da contaminanti ambientali in due specie di Teleostei(2017-11-26) Madeo, Giuseppe; Canonaco, Marcello; Brunelli, Elvira; Bernabò, IlariaItem Analisi dell'isolamento riproduttivo nelle orchidee mediterranee(2014-03-20) Scopece, Giovanni; Innocenti, Anna Maria; Musacchio, AldoItem Analisi proteomica dell'epicarpo di Limone (Citrus limon [L.] Burm.) Le qualità biochimiche del limone di Rocca Imperiale(2009) Pignataro, Vittorio; Musacchio, Aldo; Mazzuca, SilviaItem Analysis of C538T polymorphims of the SSADH gene in humans: functional and evolutionary aspects(2007) Leone,Ofelia; Passarino,Giuseppe; De Benedictis,GiovannaItem Angiotensin II and mechanisms of oxidative damage in HUVECs(2011-12-14) Carino, Annarita; Cerra, Maria Carmela; Martino, GuglielmoThe endothelium is essential for the maintenance of vascular homeostasis. Central to this role is the production of endothelium – derived nitric oxide (EDNO), synthesized by endothelial isoform of nitric oxide synthase (eNOS). Endothelial dysfunction, manifested as impaired EDNO bioactivity, is an important early event in the development of various vascular disease, including hypertension, diabetes, genesis of tumors and atherosclerosis. Endothelial dysfunction is an early feature of atherosclerosis vascular disease, characterized by a decrease in nitric oxide (NO) bioavailability and a concomitant increase in vascular superoxide (O2 . -) formation. Loss of NO bioavailability precedes the development of overt atherosclerosis and is an independent predictor of adverse cardiovascular events. Indeed, decreased NO and enhanced production of reactive oxygen species (ROS) have been recognized as major determinants of age-associated endothelial dysfunction. The degree of impairment of EDNO bioactivity is a determinant of future vascular complications. Accordingly, growing interest exists in the pathologic mechanism involved. However it is clear that immunologic mechanisms operating in the context of common cardiovascular risk factors lead to impaired endothelial function, mainly as a consequence of decreased NO bioavailability and excessive oxidative stress. The work submitted in this thesis describes on one side studies aimed to investigate cellular mechanisms underlying endothelial dysfunction and vascular damages driven by oxidative stress in the context of aging, hypertension and atherosclerosis using in vitro models. In addition, we desired to evaluate the efficacy of reducing agents such as flavonoid to monitor whether they actually have an action to recover from the cellular oxidative damage by these natural compounds and how real is their action at the level of microcirculation in vitro models. On the other side, we present studies focused on the pathophysiology of microcirculation as far as functional aspects are concerned in the context to better understand the functioning of the Renin- Angiotensin-System in particular if the Angiotensin IV is involved in mechanisms of oxidative stress and in Calcium intracellular levels.Item Approccio metodologico per lo studio di malte ed intonaci archeologici del Mediterraneo(2013-11-04) De Luca, Raffaella; Pantano, Pietro; Crisci, Gino Mirocle; Miriello, DomenicoItem Approccio multidisciplinare applicato allo studio delle interazioni tra nanoparticelle e substrati lapidei di diversa natura finalizzato alla conservazione di monumenti di interesse storico-artistico(2013-11-04) Rovella, Natalia; Pantano, Pietro; Crisci, Gino Mirocle; La Russa, Mauro FrancescoItem Arm growth and regeneration in octopus (Octopus vulgaris and Eledone moschata)(Università della Calabria, 2020-02-12) Baldascino, Elena; Cerra, Maria Carmela; Fiorito, GrazianoHere I evaluated the timing and rate of arm regeneration in octopus, a cephalopod mollusc, and contributed to the understanding of the molecular machinery involved in arm growth and regeneration in two octopus’ species: Octopus vulgaris and Eledone moschata. This work stands and revisit in part the first experimental study on arm regeneration in cephalopod molluscs, including the two species carried out by M. Lange (1920). An arm of octopus may fully regenerate and regrowth in few months after amputation. Lange recognized three stages: wound healing, tissue degeneration and tissue renewal. I applied the 3Rs principle to this study utilizing samples and data from a previous study, thus limiting the number or live animals humanely killed for the purpose of this PhD project. During the analysis of data, I found the same three stages in O. vulgaris arm regeneration to occur. I was not able to observe similar series of events in E. moschata, probably due to limited time and conditions of the animals. I found that O. vulgaris increased significantly body weight in 21 weeks. The growth appeared to be affected by repeated anesthesia, thus encouraging further studies on the physiological responses to stress in octopus. Data I analyzed confirm the view that O. vulgaris is characterized by rapid non-asymptotic growth, with high individual variability. Octopuses elongate their arms continuing to grow over time with no significant difference in the relative rate of elongation between anterior and posterior arms. The arms that underwent to regeneration, appear to have a faster growth when compared with the contralateral arms (but repeated anesthesia influenced the rate of growth of regenerating arms). Data analyzed extent the study of Lange, by providing morphometric information on the relative growth rate of the arms (regenerating vs contralateral), for the first time. A significant change in the relative expression profile of the tip vs the proximal part of the arm in O. vulgaris was observed using different approaches, confirming and extending the view that the tip the arm represents an exceptional biological system where continuous growth is achieved through massive cellular differentiation and interesting molecular events. I identified 39 genes in O. vulgaris and seven in E. moschata and studied their involvement in arm growth and/or regeneration events in octopus arms. These studies are novel.Item Arm growth and regeneration in octopus (Octopus vulgaris and Eledone moschata)(Università della Calabria, 2020-02-07) Baldascino, Elena; Cerra, Carmela; Fiorito, GrazianoItem Aspetti citotassonomici, embriologici e morfologici del genere taraxacum Wigg. (Asteraceae) in Calabria(2006) Aquaro, Gabriella; Innocenti, Anna Maria; Cesca, GiulianoItem Aspetti genetici dell'evoluzione linguistica nelle popolazioni umane: un'analisi comparativa e interdisciplinare(2017-07-12) Vigna, Mara; Pantano, Pietro; Passarino, Giuseppe; Dato, SerenaItem Azione cardiaca della catestatina in Rana esculenta(2014-03-26) Barbieri, Sandra Francesca; Canonaco, Marcello; Gattuso, Alfonsina; Mazza, RosaItem The behaviour of the glucosidase, a key enzyme in the ripening and defence response in the olive fruit (Olea europaea L.)(2007) Spadafora, Antonia; Mazzuca, Silvia; Musacchio, AldoItem Biodiversità dei carabidi e conservazione degli ambienti forestali(2014-03-25) Pulieri, Valeria; Cerra, Maria Carmela; Brandmayr, Pietro4 Abstract Resilience, stability and resistence of forest ecosystems are the main properties providing the conservation of those habitats and allowing the maintenance of processes essential for the “ecosystem services” supply. In front of climate change and other disturbances coming from human activities, it is of fundamental importance to watch and check stability status of ecosystems. Ground beetles, good bioindicators, by their community composition, functional groups and morphometric sensitivity, provide indicators on habitat conservation evaluation and contribute to identify little changes among areas looking similar. The analisys of biodiversity could be improved by considering the above factors, enhancing the functional role of single species of the community.Item Carabid beetles as natural antagonists of the olive fly Bactrocera oleae Rossi 1790(2014-03-20) Odoguardi, Rosalba; Canonaco, Marcello; Zetto, Tullia; Bonacci, TeresaItem Caratteri neotettonici del bordo nord orientale dell’Arco Calabro(2010) Folino Gallo,Michele; Russo,Franco; Tansi,CarloItem Caratterizzazione composizionale di materiali lapidei geologici ed archeologici finalizzata all'individuazione della provenienza dei litotipi del parco archeologico di Sibari(2009) Francolino, Sonia; Russo, Franco; Crisci, Gino Mirocle; Miriello, DomenicoItem Caratterizzazione del proteoma di fragola durante la maturazione ed in diversi genotipi(2013-10-24) Bianco,Linda; Musacchio,Aldo; Perrotta,Gaetano